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J Herbmed Pharmacol. 2023;12(1): 168-175. doi: 10.34172/jhp.2023.17

Original Article

In vivo and in vitro evaluation of antioxidant, antihemolytic, acute toxicity effects and high-performance liquid chromatography analysis of an aqueous extract of Moroccan Punica granatum L.

Ismail Elkoraichi 1 ORCID, Mounia Latif 1 ORCID, Othman El Faqer 1 ORCID, Rajaa Elaje 1,2 ORCID, Abderrahmane Thoume 3 ORCID, El Mostafa Mtairag 1 ORCID, Samira Rais 1,4 * ORCID, Fouad Daoudi 1 ORCID

Cited by CrossRef: 0

1- Ouadghiri Z, El Faqer O, Wahnou H, Soudassi A, Marnissi F, Rais S, Mtairag E. In Vivo and In Vitro Assessment of Marrubium vulgare: Chemical, Antioxidant and Anti-inflammatory Profiles. Arab J Sci Eng. 2025; [Crossref]
2- Lafdil F, Legssyer A, Ziyyat A, Karim A, Berraaouan A, Seddik R, Mekhfi H. Antithrombotic activity of Punica granatum, L (Pomegranate): Experimental investigation and exploration of its mechanism of action on primary and secondary hemostasis in vitro and ex vivo. Journal of Molecular Structure. 2025;1321:140195 [Crossref]
3- Lima Bezerra J, Domingos da Silva J. Dental applications of Punica granatum L. in the treatment of gingivitis: A review of ethnomedicinal uses, randomized clinical trials, and antibacterial potential against Porphyromonas gingivalis. Journal of Ethnopharmacology. 2025;336:118701 [Crossref]
4- El Faqer O, Elkoraichi I, Latif M, Debierre-Grockiego F, Ouadghiri Z, Rais S, Dimier-Poisson I, Mtairag E. Pharmacological insights into Laurus nobilis: HPLC profiling and evaluation of its anti-Toxoplasma, antioxidant, and anti-hemolytic properties. Biochemical Systematics and Ecology. 2024;117:104891 [Crossref]
5- Zemmouli N, Ramdane F, Guezzoun N. Exploring the Antioxidant, Anti-Inflammatory, and Antibacterial Properties of Green-Synthesized ZnO Nanoparticles Using Juniperusphoenicea L.. Chemistry Africa. 2025;8(3):935 [Crossref]
6- Mounia L, Ismail E, Othman E, Hicham W, Rajaa E, El Mostafa M, Mounia O, Samira R. Aframomum Melegueta: Evaluation of Chronic Toxicity, HPLC Profiling, and In Vitro/In Vivo Antioxidant Assessment of Seeds Extracts. Chemistry & Biodiversity. 2025;22(1) [Crossref]

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