Logo-jhp
J Herbmed Pharmacol. 2019;8(1): 8-13. doi: 10.15171/jhp.2019.02

Original Article

Inhibitory effect of hydroalcoholic and flavonoids extracts of Dracocephalum kotschyi, and its components luteolin, apigenin and apigenin-4’-galactoside on intestinal transit in mice

Hassan Sadraei 1 * ORCID, Seyed Mostapha Ghanadian 2, Saeideh Moazeni 1, 2

Cited by CrossRef: 8


1- Sadraei H, Sajjadi S, Asghari G, Khalili M. Effect of Matricaria chamomilla hydro-alcoholic and flavonoids rich extracts on rat isolated uterus. J Herbmed Pharmacol. 2020;9(1):35 [Crossref]
2- Hosseini-Sharifabad A, Sadraei H, Hashemnia M, Sajjadi S, Mirdamadi Z. Effect of hydroalcoholic and aqueous extracts of Dracocephalum kotschyi on bleomycin induced pulmonary fibrosis. J Herbmed Pharmacol. 2021;10(2):209 [Crossref]
3- Minaiyan M, Sadraei H, Yousefi I, Sajjadi S, Talebi A. Evaluation of the effect of hydroalcoholic and flavonoid-enriched extracts of Dracocephalum kotschyi on indomethacin-induced gastric ulcer in rats. 2021;16(2):141 [Crossref]
4- Pires J, Negri G, Duarte-Almeida J, Carlini E, Mendes F. Phytochemical analysis and investigation of analgesic, anti-inflammatory, and antispasmodic activities of hydroethanolic extracts of Alternanthera dentata, Ocimum carnosum, and Plectranthus barbatus, three species with vernacular names derived from analgesic drugs. Journal of Ethnopharmacology. 2024;334:118508 [Crossref]
5- Li Z, Zhou J, Ji L, Liang Y, Xie S. Recent Advances in the Pharmacological Actions of Apigenin, Its Complexes, and Its Derivatives. Food Reviews International. 2023;39(9):6568 [Crossref]
6- Soleimani H, Ghanadian M, Mostowfizadeh-Ghalamfarsa R. Spinach flavonoid-rich extract: Unleashing plant defense mechanisms against cucumber powdery mildew. Sustainable Chemistry and Pharmacy. 2024;41:101740 [Crossref]
7- Sadraei H, Ghanadian S, Asghari G, Gavahian A. Bronchodilator effect of apigenin and luteolin, two components of Dracocephalum kotschyi on isolated rabbit trachea. J Herbmed Pharmacol. 2019;8(4):281 [Crossref]
8- Sadraei H, Sajjadi S, Tarafdar A. Antispasmodic effect of hydroalcoholic and flavonoids extracts ofDracocephalum kotschyion rabbit bladder. J Herbmed Pharmacol. 2020;9(2):145 [Crossref]
9- Mapesa W, Waweru M, Bukachi F, Wafula K. Aqueous Tuber Extracts of Tylosema fassoglense (Kotschy ex Schweinf.) Torre and Hillc. (Fabaceae). Possess Significant In-Vivo Antidiarrheal Activity and Ex-Vivo Spasmolytic Effect Possibly Mediated by Modulation of Nitrous Oxide System, Voltage-Gated Calcium Channels, and Muscarinic Receptors. Front Pharmacol. 2021;12 [Crossref]
10- Ayele T, Abebe E, Muche Z, Agidew M, Yimer Y, Addis G, Baye N, Kassie A, Alemu M, Yiblet T, Tiruneh G, Dagnew S, Moges T, Tadesse T, Zelalem A. In vivo antidiarrheal activity of the crude extract and solvent fractions of Rhamnus prinoides (Rhamnaceae) leaves. Heliyon. 2023;9(6):e16654 [Crossref]
11- Karim A, Malek S, Marghich M, Amrani O, Addous A, Beyi L, Aziz M. Antidiarrheal and antispasmodic effects of methanol fraction of Ammodaucus leucotrichus in gastrointestinal problems: an integrative medicine approach. J Smooth Muscle Res. 2024;60(0):39 [Crossref]
12- Sadraei H, Rasouli-Amirabadi A, Yekdaneh A, Tavakoli N. Bioassay standardization of drug dosage form prepared from hydroalcoholic extract of Dracocephalum kotschyi . J Herbmed Pharmacol. 2022;11(3):435 [Crossref]