Logo-jhp
J Herbmed Pharmacol. 2023;12(3): 331-336.
doi: 10.34172/jhp.2023.35

Scopus ID: 85164212252
  Abstract View: 2317
  PDF Download: 1044

Review

Moringa oleifera and its application in dental conditions: A systematic review and meta-analysis

Moumita Das ORCID logo, Nihar Ranjan Panda ORCID logo, Ruchi Bhuyan* ORCID logo, Sanat Kumar Bhuyan ORCID logo

1 Department of Medical Research, IMS and SUM Hospital, Siksha ‘O’ Anusandhan (Deemed to be University), Bhubaneswar, India
*Corresponding Author: Ruchi Bhuyan, Email: ruchibhuyan@soa.ac.in

Abstract

Moringa oleifera is a considerable ethnomedical herb with various bioactive compounds. This study aimed to analyze the efficacy of M. oleifera in the prevention and management of various oral conditions. A thorough search was conducted on the Web of Science, Scopus, PubMed, and PubMed Central databases. After screening the data on the basis of inclusion and exclusion criteria, 9 studies were considered for further meta-analysis. The analysis was performed on R programming software (version R-4.0.2) and the results were represented by a forest plot. The estimate obtained via common and random effects model for in vitro studies was statistically insignificant (I2 test P > 0.05) with risk ratios of 8.25 (95% CI: 3.76-18.08) and 7.98 (95% CI: 3.64-17.50) and for in vivo studies were statistically significant (I2 test P )0.05 < with risk ratios of 1.12 (95% CI: 0.90-1.40) and 0.97 (95% CI: 0.71-1.32), indicating the efficacy of M. oleifera in oral diseases on animal and clinical trials, whereas it failed to report the efficacy on in vitro level. Future research has to be done to come up with new and more phytoactive compounds from all parts of the plant with proper extraction procedures. The effectiveness of the compounds has to be validated first on in vitro scale followed by clinical trials so that M. oleifera can be used as therapy in preventing and managing oral ailments.

Implication for health policy/practice/research/medical education:

This meta-analysis demonstrated that Moringa oleifera had applications in different oral conditions like periodontitis, root canal infection, gingivitis, dental caries, oral cancer, etc.

Please cite this paper as: Das M, Panda NR, Bhuyan R, Bhuyan SK. Moringa oleifera and its application in dental conditions: A systematic review and meta-analysis. J Herbmed Pharmacol. 2023;12(3):331-336. doi: 10.34172/jhp.2023.35.

First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 2318

Your browser does not support the canvas element.


PDF Download: 1044

Your browser does not support the canvas element.

Submitted: 03 Nov 2022
Revision: 24 Feb 2023
Accepted: 26 Feb 2023
ePublished: 01 Jun 2023
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)