Logo-jhp
  Abstract View: 81

Review

Mallotus philippensis (Lam.) Müll. Arg.: A review on its pharmacology and phytochemistry

Abhishek Kumar 1 ORCID logo, Meenu Patil 1 ORCID logo, Pardeep Kumar 1 ORCID logo, Ram Chand Bhatti 1 ORCID logo, Rupinder Kaur 1 ORCID logo, Nitin Kumar Sharma 2 ORCID logo, Anand Narain Singh 1* ORCID logo

1 Department of Botany, Panjab University, Chandigarh-160014, India
2 Department of Botany, Govt. College Amb, Una, Himachal Pradesh-177203, India

Abstract

Kamala tree (Mallotus philippensis) is traditionally used by different ethnic groups to treat a variety of diseases and health ailments. However, these traditional uses need to be scientifically investigated and validated in order to develop drugs from this tree. Therefore, the present article is aimed to review the scientifically validated knowledge on the pharmacology and phytochemistry of the tree. To accomplish this, we extensively surveyed the available databases like Scopus, Web of Science, Google Scholar, ScienceDirect, NCBI including PubMed and PubChem, etc. by using keywords ‘Mallotus philippensis’, ‘Mallotus phillippinensis’ and ‘Mallotus philippinensis’. Our results indicated that the tree possesses more than 50 different types of important phytochemicals of natural origin. The wide array of phytochemicals possesses fascinating biological activities like anthelmintic, antibacterial, anti-inflammatory, anti-oxidant, anti-cancerous, anti-tuberculosis, anti-parasitic, analgesic, anti-urolithiatic and anti-viral activities. Thus, pharmacological activities and isolation of active phytochemicals make the tree a promising candidate for drug discovery. However, pharmacological activities such as antibacterial and anti-oxidant activities are often tested with crude extracts and in vitro rudimentary methods that can be sometimes misleading and non-specific. Thus, more sophisticated techniques may be applied for the isolation of active chemicals and elucidating their mechanism of actions.
Keywords: Kamala tree, Mallotus philippensis, Ethnomedicinal uses, Pharmacology, Phytochemistry, Rottlerin
This review article presented the progress of scientific investigations and validation of traditional uses of the Kamala tree (Mallotus philippensis). Antimicrobial properties of the tree are extensively investigated whereas other pharmacological properties like anthelminthic, anti-viral, anti-urolithiatic etc, still need to be investigated. Specifically, the active phytochemicals such as Rottlerin and Mallotophilippens can be novel drugs for the treatment of cancer and tuberculosis in future.
First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 81

Your browser does not support the canvas element.


PDF Download: 0

Your browser does not support the canvas element.

Submitted: 21 Sep 2019
Revision: 04 Nov 2019
Accepted: 04 Nov 2019
ePublished: 20 Oct 2020
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)