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Original Article
Majid Asadi-Samani ORCID, Dhiya Altememy ORCID, Aziz H. Jasim ORCID, Javad Saffari-Chaleshtori* ORCID, Mohammad-Taghi Moradi* ORCID
J Herbmed Pharmacol. 2023;12(4): 453-458. doi: 10.34172/jhp.2023.42334
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The results of this study can be used for the appropriate understanding of the drug's effect mechanism on the virus neuraminidase from the perspective of molecular dynamics and assist researchers in the design and production of anti-influenza drugs.

Original Article
Kehinde oluwakemi Fagbemi* ORCID, Olufunmiso Olusola Olajuyigbe ORCID, Rogers Coopoosamy ORCID
J Herbmed Pharmacol. 2023;12(4): 459-468. doi: 10.34172/jhp.2023.43430
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The synthesized SNPs mediated from T. indica showed significant radical scavenging potentials and a strong inhibitory effect on some pathogenic organisms. This study can be expanded to include an in vivo assay to acquire robust evidence on the effectiveness of SNP mediated from this fruit in the biological environment. The findings could be used as an alternate solution to herbal medicine to treat oxidative stress-related health issues and for the production of antibiotics.

Original Article
Nur 'Ainun Mokhtar* ORCID, Fatahiya Mohamed Tap ORCID, Nur Hannani Ahmad Rozani ORCID, Nurul Bahiyah Ahmad Khairudin* ORCID, Roshafima Rasit Ali ORCID
J Herbmed Pharmacol. 2023;12(4): 469-482. doi: 10.34172/jhp.2023.44672
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This study provides insight into Chromolaena odorata’s valuable phytochemical compounds. Molecular docking as well as adsorption, distribution, metabolism, and excretion (ADME) prediction performed in this study provide more evidence of C. odorata’s wound-healing potential by elucidating its inhibitory activity against pivotal protein targets during the inflammation, proliferation, and remodeling stages of wound healing. The information presented in this paper serves as preliminary data for any wound healing product planned to be prepared with C. odorata extracts or any of its phytoconstituents.

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Licorice root extract may be a promising prophylactic remedy against acute pancreatitis and acute lung injury.

Original Article
Hong Hanh Nguyen ORCID, Ngan Hoang Nguyen ORCID, Tu Thi Thanh Nguyen* ORCID
J Herbmed Pharmacol. 2023;12(4): 492-499. doi: 10.34172/jhp.2023.44843
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Our findings revealed that an extract mixture of C. chrysantha and G. pentaphyllum could reduce blood lipid indices and increase HDL-C levels in the rat atherosclerotic blood, indicating that this mixture is a potential source of natural agents for atherosclerosis treatment.

Original Article
Sarath Kumar ORCID, Kavitha Sanjeev ORCID, Nagarathinam Sundaramoorthy* ORCID, Sekar Mahalaxmi ORCID
J Herbmed Pharmacol. 2023;12(4): 500-504. doi: 10.34172/jhp.2023.44919
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Gallic Acid can be a preferred final irrigating solution during chemo-mechanical preparation when employing the resin-based AH Plus sealer. The higher bond strength of the sealer to root dentin signifies improved sealing ability, which results in less microleakage.

Original Article
Pedram alimosazadeh ORCID, Mohd Sajjad Ahmad Khan ORCID, Seyed Javad Sanei* ORCID
J Herbmed Pharmacol. 2023;12(4): 505-511. doi: 10.34172/jhp.2023.45000
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Our findings showed the significant variations of phytochemical profiles and anti-candidal capacities of olive leaves by harvest time and type of cultivar, and spring leaves were suggested as the best raw materials for pharmaceutical industries. The results also emphasized the broad antifungal sensitivity pattern of Candida albicans strains to olive leaf extracts.

Original Article
Phanida Suphiratwanich ORCID, Benjaporn Buranrat ORCID, Supavadee Boontha* ORCID
J Herbmed Pharmacol. 2023;12(4): 512-520. doi: 10.34172/jhp.2023.45002
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This study provides novel insights into the anti-cancer effects of extracts prepared from the leaves of broad and spirale cultivars of C. variegatum on breast (MCF-7), hepatoma (HepG2), and cervical (HeLa) cancer cell lines and their effective uses in treating hepatoma, breast, and cervical cancers.

Original Article
Nazir Ahmad ORCID, Kaisun Nesa Lesa ORCID, Navista Sri Octa Ujiantari ORCID, Ari Sudarmanto ORCID, Zullies Ikawati ORCID, Nanang Fakhrudin* ORCID
J Herbmed Pharmacol. 2023;12(4): 521-535. doi: 10.34172/jhp.2023.45004
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This study suggests that WCE has the potency to improve memory function by blocking PDE1B and can contribute to the development of pharmaceutical agents derived from natural resources to improve memory function.

Original Article
Mohamed Jeddi ORCID, Zineb Benziane Ouaritini ORCID, Rachida Shita ORCID, Kawtar Fikri-Benbrahim* ORCID
J Herbmed Pharmacol. 2023;12(4): 536-548. doi: 10.34172/jhp.2023.46047
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This work reports the ethnopharmacology of Salvia officinalis, Dittrichia viscosa, and Daucus carota in Northern Morocco. It provides a detailed insight into their bioactive compounds, which could serve the pharmaceutical industries, as active ingredients to develop innovative safe drugs.

Original Article
Parichart Kwaengmuang ORCID, Koravich Chaiyawong ORCID, Todsapon Warong ORCID, Sakulrat Rattanakiat ORCID, Pawitra Pulbutr* ORCID
J Herbmed Pharmacol. 2023;12(4): 549-559. doi: 10.34172/jhp.2023.46056
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This study provides scientific evidence that the combination of lupinifolin (8 µg/mL) and antibacterial drugs acting as protein synthesis inhibitors, specifically tetracycline, streptomycin, and clindamycin, at their sub-MICs, can significantly inhibit MRSA biofilm formations. These findings suggest the potential use of lupinifolin as an enhancer against MRSA biofilm formation.

Original Article
Vijayaragavan Haripriya ORCID, Mahalaxmi Sekar ORCID, Sampath Vidhya* ORCID, Purushothaman Vanajassun Pranav ORCID
J Herbmed Pharmacol. 2023;12(4): 560-566. doi: 10.34172/jhp.2023.46064
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This in vitro study showed the promising antibacterial effects of curcumin, allicin, gingerol, and cinnamon against Enterococcus faecalis. Future studies should focus on harnessing the advantages of these natural medicaments in endodontic disinfection.

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The current study presents scientific evidence that supports the efficacy of a spray gel formulation containing banana peel extract as an antimicrobial agent. This particular spray gel formulation also promoted the faster healing of burn wounds in rabbits. As a result, the banana (M. paradisiaca) peel spray gel exhibits promising potential as an effective medicinal treatment for facilitating wound healing.

Original Article
Nha Thao Nguyen Ngoc* ORCID, Duc Linh Vo ORCID, Duy Khanh Dang ORCID, Trung Hieu Huynh ORCID, Cao Thien Ha ORCID
J Herbmed Pharmacol. 2023;12(4): 575-584. doi: 10.34172/jhp.2023.48081
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The extracts from mango seed possessed antibacterial and anti-inflammatory activities. However, further clinical examination should be performed to approve these effects.

Original Article
Behzad Imani ORCID, Sahar Alizade* ORCID, Salman Khazaei ORCID, Pouran Hajian ORCID
J Herbmed Pharmacol. 2023;12(4): 585-591. doi: 10.34172/jhp.2023.46050
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This clinical trial showed that ginger might be useful in preventing nausea and vomiting caused by cesarean section as a possible natural remedy.

Short Communication
Mahdi Aghaei* ORCID, Farhod Alizadegan ORCID, Yosra Raziani ORCID, Githa Kishore ORCID, Massumeh Saadatmand ORCID, Suja Ajoy Kumar ORCID
J Herbmed Pharmacol. 2023;12(4): 592-596. doi: 10.34172/jhp.2023.44897
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We reported the favorable antileishmanial effects of 7HMI against L. major with possible mechanisms such as reducing the infectivity rate of macrophage cells and provoking NO creation. Hence, 7HMI might be considered for preparation of a new drug against L. major Nevertheless, more researches must be performed to determine its efficacy in vivo and clinical subjects.