J Herbmed Pharmacol. 2021;10(2): 149-155.
doi: 10.34172/jhp.2021.16
  Abstract View: 913
  PDF Download: 436


Heartburn and effective herbal remedies: A systematic review study in Iranian ethnobotanical documents

Gholam Basati 1 ORCID logo, Pardis Ghanadi 2 ORCID logo, Pegah Shakib 3 ORCID logo, Majid Hamidi 4* ORCID logo, Peyman Amanolahi Baharvand 5 ORCID logo

1 Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran
2 Medical Student, Lorestan University of Medical Sciences, Khorramabad, Iran
3 Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khoramabad, Iran
4 Department of Pediatrics, Shahrekord University of Medical Sciences, Shaharekord, Iran
5 Department of English, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran


Every year, millions of people worldwide get sick with gastrointestinal diseases such as heartburn. Certain herbs contribute to the alleviation of heartburn, nausea, and improvement of digestion. Moreover, these herbs do not have as many side effects as synthetic drugs. As a health problem and one of the challenging issues in medical sciences, heartburn is common in children and adults worldwide. Hence, in the present study, we tried to report medicinal plants used in cultures and traditions of different regions of Iran to treat heartburn in children and adults. In this review study, articles of Iranian ethnobotanical sources were searched with the keywords of ethnobotanics, heartburn, children, adult, medicinal plants, and Iran. Journal articles published from 2010 to 2019 in several Iranian and International databases, including ISI Web of Science, PubMed, Scopus, ISC, Magiran, were searched to find relevant articles and information. Anethum graveolens L., Punica granatum L., Mentha pulegium, Thymus kotschyanus Boiss. & Hohen., Achillea millefolium, Ocimum basilicum, Nigella sativa, etc., are the plants used in different parts of Iran to treat heartburn.
Keywords: Digestive problem, Heartburn, Anethum graveolens, Mentha pulegium, Medicinal plants, Ethnobotany, Iran
This review provides a detailed insight into the medicinal plants effective on heartburn and shows that Iranian ethnobotanical sciences provide a list of natural treatments for heartburn, which can be used as a reliable source for preparation of new drugs for children and adult.
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Submitted: 04 May 2020
Revision: 21 Sep 2020
Accepted: 21 Sep 2020
ePublished: 05 Jan 2021
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