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J Herbmed Pharmacol. 2020;9(3): 200-208.
doi: 10.34172/jhp.2020.26
  Abstract View: 136
  PDF Download: 91

Original Article

Antioxidant and scolicidal activities of four Iranian Mentha species (Lamiaceae) in relation to phenolic elements

Mojtaba Ranjbar 1* ORCID logo, Mahmoud Kiani 2 ORCID logo, Ali Nikpay 3 ORCID logo

1 Faculty of Biotechnology, Amol University of Special Modern Technologies, Amol, Iran
2 Faculty of Medicinal Plants, Amol University of Special Modern Technologies, Amol, Iran
3 Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol, Iran
*Corresponding author: Mojtaba Ranjbar, Email: ranjbarf@ausmt.ac.ir

Abstract

Introduction: There is a growing interest of industry to replace synthetic chemicals by natural products with bioactive properties from plant origin. The present study reported the antioxidant activity and scolicidal effects of the crude extracts from Mentha spicata, M. aquatica, M. longifolia, and M. × piperita var. citrata growing in Iran.

Methods: Total phenolic, flavonoid and flavonol contents of the four Mentha taxa were examined. Two antioxidant assays i.e. free radical scavenging activity (DPPH assay) and reducing power assay were used for determining the antioxidant capacity of the alcoholic extracts. Scolicidal activity of serial dilutions (15–200 mg/mL) of Mentha extracts was evaluated after 1, 5, 10, 20 and 30 minutes of exposure time.

Results: Methanol was the solvent yielding the highest values of total phenolic (TPC), flavonoid (TFC) and flavonol contents (TFvC). On the other hand, the extracts from M. × piperita var. citrata gave the highest total phenolic content (191.6 mg gallic acid equivalent per g; GAE/g), total flavonoid content (57.0 mg quercetin per g; QE/g) and total flavonol content (15.3 mg QE/g) values. The methanol extracts of M. × piperita var. citrata also gave the strongest DPPH radical scavenging activity (83.2%), whereas the reducing power yielded absorbance values between 0.189 in M. spicata and 1.16 in M. × piperita var. citrata. The highest scolicidal activity (99.54%) was observed in 200 mg/mL methanol extract of M. aquatica after 30 minutes of application.

Conclusion: Overall, M. × piperita var. citrata and M. aquatica could be the taxa of choice for future supplementary studies.

Keywords: Antioxidant, Flavonoid, Mentha, Phenolic compounds, Scolicidal effect

Implication for health policy/practice/research/medical education:

Extracts of Mentha species exhibited potent antioxidant and scolicidal activities, which may have significant implications for the future development of anti-parasitic drugs derived from Mentha species.

Please cite this paper as: Ranjbar M, Kiani M, Nikpey A. Antioxidant and scolicidal activities of four Iranian Mentha species (Lamiaceae) in relation to phenolic elements. J Herbmed Pharmacol. 2020;9(3):200-208. doi: 10.34172/jhp.2020.26

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Submitted: 11 Jun 2019
Accepted: 05 Oct 2019
ePublished: 02 May 2020
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