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J Herbmed Pharmacol. 2014;3(2): 83-86.
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Original Article

Identification of chemical compounds of Nardostachys Jatamansi essence available in Iran

Nasrolah Ghassemi-Dehkordi 1, Ebrahim Sajjadi 1, Hamed Shafiei-Koojani 1 * , Mahtab Keshvari 2, Seyyed-Masih Hoseini 3

1 Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
2 Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
3 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
*Corresponding author: Hamed Shafiei-Koojani, hamedshafiei1366@gmail.com

Abstract

Introduction: With regard to using drugs with plant origin and with the aim of suitable use of these types of drugs and preventing them to be abused, it is necessary to determine the standards of these plants. The aim of the present study was to identify and study chemical compounds of Nardostachys Jatamansi essence in Iran and define monograph of this plant for the Iranian plant pharmacopeia.

Methods: In an experimental study the Nardostachys Jatamansi specimen was prepared from the market in Iran. The essence of the plant was prepared by the hydro-distillation in Clevenger apparatus. Essence was obtained as a greenish yellow oil layer with the 0.07 % yield. The essence compounds were identified quantitatively by Gas Chromatography-Mass Spectroscopy (GC/MS) method.

Results: Totally, 29 compounds were identified in Nardostachys Jatamansi essence. The retention indexes (RI) were only similar with overall standard values in two compounds like mesitylene and P-cymene. In this line the RI values about three compounds of valerenic acid, palmitic acid, and valerenyl isovalerate were determined significantly higher than standard values of RI.

Conclusion: The essence prepared from the Nardostachys Jatamansi plant in Iran was different in terms of some compounds and components including valerenic acid, palmitic acid, and valerenyl isovalerate and so it is necessary to identify and register quality and quantity characteristics of compounds available in this plat in the Iranian medicinal plants pharmacopeia.

Keywords: Essence, Nardostachys Jatamansi, Iran, Retention index

Implication for health policy/practice/research/medical education:

The essence prepared from Nardostachys Jatamansi plant in Iran seems to be different in terms of some compounds and components. So it is necessary to identify and register quality and quantity characteristics of compounds available in this plat in the Iranian medicinal plants pharmacopeia.

Please cite this paper as: Ghassemi-Dehkordi N, Sajjadi E, Shafiei-Koojani H, Mahtab Keshvari, Hoseini SM. Identification of chemical compounds of Nardostachys Jatamansi essence available in Iran. J Herbmed Pharmacol. 2014; 3(2):83-86.

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ePublished: 01 Dec 2014
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