J Herbmed Pharmacol. 2019;8(2):85-89.
doi: 10.15171/jhp.2019.14
  Abstract View: 66
  PDF Download: 80

Mini Review

A mini-review on phytochemistry and pharmacological activities of Scrophularia striata

Pari Tamri 1, 2 * ORCiD

1 Department of Pharmacology and Toxicology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran
2 Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran

Abstract

Introduction: Scrophularia striata (Scrophulariaceae) is an important medicinal plant in Iran and in Iranian folk medicine it has been used for variety of disorders. The present article aims to provide a review at the studies done on phytochemistry and pharmacological effects of S. striata. Methods: This mini review is based on a literature study of scientific journals from electronic sources, such as Science Direct, PubMed, Google Scholar, Scopus and Web of Science. Results: The main chemical constituents which have been isolated and identified from Scrophularia striata are cinnamic acid, some flavonoids such as quercetin, isorhamnetin3-O-rutinoside and nepitrin and one glycoside (acteoside1) . This plant possesses antiinflammatory , antibacterial , antioxidant, anticancer, analgesic and neuroprotective effects. In addition it accelerates wound healing process Conclusion : Scrophularia striata has a potential for the treatment of several diseases and disorders, but there are only a few studies done to investigate the plant phytochemistry, thus f urther studies should be focused on isolation and identification of active compounds with pharmacological activities. Besides, the majority of pharmacological studies have been performed using aerial parts of plant , thus further studies are needed to investigate bioactivity of other parts of the plant.
Introduction: Scrophularia striata (Scrophulariaceae) is an important medicinal plant in Iran and in Iranian folk medicine it has been used for variety of disorders. The present article aims to provide a review at the studies done on phytochemistry and pharmacological effects of S. striata.Methods: This mini review is based on a literature study of scientific journals from electronic sources, such as Science Direct, PubMed, Google Scholar, Scopus and Web of Science.Results: The main chemical constituents which have been isolated and identified from Scrophularia striata are cinnamic acid, some flavonoids such as quercetin, isorhamnetin-3-O-rutinoside and nepitrin and one glycoside (acteoside1) . This plant possesses anti-inflammatory , antibacterial , antioxidant, anticancer , analgesic and neuroprotective effects. In addition it accelerates wound healing processConclusion : Scrophularia striata has a potential for the treatment of several diseases and disorders, but there are only a few studies done to investigate the plant phytochemistry, thus further studies should be focused on isolation and identification of active compounds with pharmacological activities . Besides, the majority of pharmacological studies have been performed using aerial parts of plant , thus further studies are needed to investigate bioactivity of other parts of the plant.
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Submitted: 22 Oct 2018
Revised: 04 Dec 2018
Accepted: 24 Jan 2019
First published online: 26 Feb 2019
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